Efeitos do consumo proteico sobre a hipertrofia ocasionada pelo treinamento resistido: uma visão atual

  • Santiago Tavares Paes Universidade Federal de Juiz de Fora
Palavras-chave: Ingestão proteica, Exercício resistido, Hipertrofia, Exercício físico, Nutrição

Resumo

Objetivo: Levantar, discutir e sintetizar as pesquisas que analisaram os efeitos do consumo proteicosobre a hipertrofia muscular ocasionada pelo treinamento resistido.Fontes de dados: A pesquisa foi realizada nas bases de dados do Pubmed. Os descritores utilizados foram: Protein consumption, Protein intake, Resistance exercise, Resistance trainning, Hypertrophy, Exercise, Nutrition.Síntese dos dados: O rastreamento dos estudos utilizando os descritores encontrou 73195 estudos. Após cruzamento entre os descritores, obteve-se 4.412 estudos. Desses, depois de realizada análise dos títulos dos estudos, foram cogitados 502 relevantes referências; Após leitura dos resumos 120 estudos foram selecionados, sendo então submetidos aos critérios de inclusão/exclusão, totalizando, ao final, 47 estudos, lidos integralmente. A maioria dos estudos relacionou a prática do treinamento resistido e a capacidade de síntese de proteínas musculares cujo efeito está associado, entre outros fatores nutricionais, a ingestão de quantidades diárias relativamente maiores de proteínas de alta qualidade aminoacídica.Conclusões: A prática de treinamento resistido é capaz de potencializar a síntese de proteínas musculares aguda e cronicamente. Atletas que realizam essa modalidade necessitam consumir uma quantidade diária relativamente maior de proteínas ricas em aminoácidos essenciais para recuperar o dano tecidual muscular ocasionado pelo treino. O consumo aproximado de 20-25g de proteínas, preferencialmente com valores significativos de leucina, parecem potencializar a síntese e recuperação miofibrilar especialmente no pós-treinamento, entretanto a magnitude da hipertrofia ocasionada por esse tipo de exercício é também influenciada por fatores metabólicos, tensionais e hormonais.

Referências

-Antonio, J.; Peacock, C. A.; Ellerbroek, A.; Fromhoff, B.; Silver, T. The effects of consuming a high protein diet (4.4 g/kg/d) on body composition in resistance-trained individuals. Journal of the International Society of Sports Nutrition. Vol. 11. Num.19. 2014.

-Aparicio, V. A.; Nebot, E.; G. Kapravelou, J. M.; Sánchez, C.; Porres, J.M.; Jurado, M. L.; Aranda, P. El entrenamiento de fuerza reduce la acidosis metabólica y la hipertrofia hepática y renal consecuentes del consumo de una dieta hiperproteica en ratas. Nutricion Hospitalaria. Vol. 26. Num. 6. p. 1478-1486. 2011.

-Aparicio, V. A.; Sánchez, C.; Ortega, F. B.; Nebot, E.; G. Kapravelou, J. M.Porres, J.M.; Aranda, P. Effects of the dietary amount and source of protein, resistance training and anabolic-androgenic steroids on body weight and lipid profile of rats. Nutricion Hospitalaria. Vol. 28. Num. 1. p. 127-136. 2013.

-Areta, J. L.; Burke, L. M.; Ross, M. L.; Camera, D. M.; West, D. W.D.; Broad, E. M.; Jeacocke, N. A.; Moore, D. R.; Stellingwerff, T.; Phillips, S. M.; Hawley, J. A.; Coffey, G. V. Timing and distribution of protein ingestion during prolonged recovery from resistance exercise alters myofibrillar protein synthesis. J Physiol. Vol. 591. Num. 9. p. 2319-2331. 2013.

-Beelen, M.; Tieland, M.; Gijsen, A. P.; Vandereyt, H.; Kies, A. K.; Kuipers, H.; Saris, W. H. M.; Koopman, R.; Van Loon, L. J. C. Coingestion of carbohydrate and protein hydrolysate stimulates muscle protein synthesis during exercise in young men, with no further increase during subsequent overnight recovery. The Journal of Nutrition. Vol. 138. p. 2198-2204. 2008.

-Blaauw, B.; Schiaffino, S.; Reggiani, C. Mechanisms Modulating Skeletal Muscle Phenotype. Compr Physiol. Vol. 3. p. 1645-1687. 2013.

-Bolster, D. R.; Crozier, S. J.; Kimball, S. R.; Jeferson, L. S. AMP activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling. J Biol Chem. Vol. 277. p. 23977-23980. 2002.

-Borsheim, E.; Cree, M. G.; Tipton, K. D.; Elliot, T. A.; Aarsland, A.; Wolfe, R. R. Effect of carbohydrate intake on net muscle protein synthesis during recovery from resistance exercise. Journal of Apply Physiology. Vol. 96. p. 674-678. 2004.

-Bosse, J. D.; Dixon, B. M. Dietary protein to maximize resistance training: a review and examination of protein spread and change theories. Journal of the International Society of Sports Nutrition. Vol. 9. Num. 42. 2012.

-Burd, N. A.; West, D. W. D.; Staples, A. W.; Atherton, P. J.; Baker, J. M.; Moore, D. R.; Holwerda, A. M.; Parise, G.; Rennie, M. J.; Baker, s. K.; Phillips, S. M. Low-Load High Volume Resistance Exercise Stimulates Muscle Protein Synthesis More Than High-Load Low Volume Resistance Exercise in Young Men. Plos One. Vol. 5. Num. 8, 2010.

-Burke, L. M.; Hawley J. A.; Ross M. L.; Moore, D. R.; Phillips, S. M.; Slater, G. R.; Stellingweff, T.; Tipton, K. D.;Garnham, A. P.; Coffey, V. G. Pre exercise aminoacidemia and muscle protein synthesis after resistance exercise. Med Sci Sports Exerc. Vol. 44. Num. 10. p. 1968-1977. 2012.

-Churchward-Venne, T. A.; Burd, N. A.; Phillips, S. M. Nutritional regulation of muscle protein synthesis with resistance exercise: strategies to enhance anabolism. Nutrition & Metabolism. Vol. 9. Num. 40. 2012.

-Crozier, S. J.; Kimball, S. R.; Emmert, S. W.; Anthony, J. C.; Jefferson, L. S. Oral leucine administration stimulates protein synthesis in rat skeletal muscle. The Journal of Nutrition. Vol. 135. p. 376-382. 2005.

-Denne, S. C.; Liechty, E. A.; Liu, Y. M.; Brechtel, G.; Baron, A. D. Proteolysis in skeletal-muscle and whole-body in response to euglycemic hyperinsulinemiain normal adults. American Journal of Physiology. Vol. 261. p. 809-814. 1991.

-Egan, B.; Zierath, J. R. Exercise Metabolism and the Molecular Regulation of Skeletal Muscle Adaptation. Cell Metabolism. Vol. 5. Num.17. p.162-184. 2013.

-Glynn, E. L.; Fry, C. S.; Drummond, M. J.; Dreyer, H. C.; Dhanani, S.; Volpi, E.; Rasmussem, B. B. Muscle protein breakdown has a minor role in the protein anabolic response to essential amino acid and carbohydrate intake following resistance exercise. Am J Physiol RegulIntegr Comp Physiol. Vol. 299. p. 533-540. 2010.

-Glynn, E. L.; Fry, C. S.; Timmerman, K. L.; Drummond, M. J.; Volpi, E.; Rasmussen, B. B. Addition of carbohydrate or alanine to an essential amino acid mixture does not enhance human skeletal muscle protein anabolism. The Journal of Nutrition. Vol. 143. p. 307-314. 2013.

-Green, K. K.; Shea, J. L.; Vasdev, S.; Randell, E.; Gulliver, W.; Sun, G: Higher dietary protein intake is associated with lower body fat in the Newfoundland Population. Clin Med Insights Endocrinol Diabetes. Vol. 3. p. 25-35. 2010.

-Greenhaff P. L.; Karagounis, L.; Peirce, N; Simpson, E.J.; Hazell,M.; Layfield, R.; Wackerhage, H.; Smith, K.; Atherton, P.; Selby, A.; Rennie, M. J. Disassociation between the effects of amino acids andinsulin on signalling, ubiquitin-ligases and protein turnover in human muscle. Am J Physiol Endocrinol Metab. Vol. 295. p. 595-604. 2008.

-Guimarães-Ferreira, L.; Cholewa J.; Naimo, M. A.; Zhi, X; Magagnin, D.; Dal Ponte de Sá, R. B.; Streck, E. L.; Silva Teixeira, T.; Zanchi, N. E. Resistance training and protein intake synergistic effects: Practical aspects. Nutrition. 2014.

-Helms, E. R.; Aragon, A. A.; Fitschen, P. J. Evidence-based recommendations for natural bodybuilding contest preparation: nutrition and supplementation. Journal of the International Society of Sports Nutrition. Vol. 11. Num. 20. 2014.

-Helms, E. R.; Zinn C.; Rowlands, D. S.; Brown, S. R. A Systematic Review of Dietary Protein During Caloric Restriction in Resistance Trained Lean Athletes: A Case for Higher Intakes. International Journal of Sport Nutrition and Exercise Metabolism. Vol. 4. p. 127-138. 2014.

-Herring, S. A.; Kibler, W. B.; Putukian, M. Selected Issues for Nutrition and the Athlete: A Team Physician Consensus Statement. Medicine & Science and Sports & Exercise. Vol. 45. Num.12. p. 2378-2386. 2013.

-Jewell, J. L.; RusselR. C., Guan, K. Amino acid signalling upstream of mTOR. Nat Rev Mol Cell Biol. Vol.14. Num. 3. p. 133-139. 2013.

-Katsanos, C. S.; Kobayashi, H.; Sheffield-Moore, M. Aarsland, A.; Wolfe, R. R. A high proportion of leucine is required for optimal stimulation of the rate of muscle protein synthesis by essential amino acids in the elderly. Am J Physiol Endocrinol Metab. Vol. 291. p. 381-387. 2006.

-Koopman, R.; Beelen, M.; Stellingwerff, T.; Pennings, B.; Saris, W. H.; Kies, A. K.; Kuipers, H.; Loon, L. J. Coingestion of carbohydrate with protein does not further augment post-exercise muscle protein synthesis. American Journal of Physiology Endocrinology Metabolism. Vol. 293. p. 833-842. 2007.

-Kumar, V.; Selby, A.; Rankin, D.; Patel, R.; Atherton, P.; Hildebrandt, W.; Williams, J.; Smith, K.; Seynnes, O.; Hiscock, N.; Rennie, M. J. Age-related differences in the dose–response relationship of muscle protein synthesis to resistance exercise in young and old men. J Physiol. Vol. 587. p. 211–217. 2009.

-Mitchell, C. J.; Churchward-Venne, T. A.; West, D. W. D.; Burd, N. A; Breen, L.; Baker, S. K.; Phillips, S. M. Resistance exercise load does not determine training mediated hypertrophic gains in young men. J Appl Physiol. Vol. 113. p. 71-77. 2012.

-Mitchell, C. J.; Churchward-Venne, T. A.; Bellamy, L.; Parise, G.; Baker, S. K.; Phillips, S. M. Muscular and Systemic Correlates of Resistance Training-Induced Muscle Hypertrophy. Plos One. Vol. 8. Num. 10. 2013.

-Moore, D. R.; Robinson, M. J.; Fry, J. L.; Tang, J. E.; Glover, E. I.; Wilkinson, S. B.; Prior T.; Tarnopolsky, M. A.; Phillips, S. M. Ingested protein dose response of muscle and albumin protein synthesis after resistance exercise in young men. American Journal of Clinical Nutrition. Vol. 89. p. 161-168. 2009.

-Pasiakos, S. M. Exercise and Amino Acid Anabolic Cell Signaling and the Regulation of Skeletal Muscle Mass. Nutrients. Vol. 4. p. 740-758. 2012.

-Phillips, S. M. Physiologic and molecular bases of muscle hypertrophy and atrophy: impact of resistance exercise on human skeletal muscle (protein and exercise dose effects). Apply Physiology Nutrition Metabolism. Vol. 34. p. 403-410. 2009.

-Phillips, S. M. Protein requirements and supplementation in strength sports. Nutrition. Vol. 20. p. 689-695. 2004.

-Phillips, S.M.;Van Loon, L.J. Dietary protein for athletes: from requirements to optimum adaptation. Journal of Sports Sciences. Vol. 29 (Suppl. 1). p. 29-38. 2011.

-Poortmans, J. R.; Carpentier, A.; Pereira-Lancha, L. O.; Lancha Jr., A. Protein turnover, amino acid requirements and recommendations for athletes and active populations. Brazilian Journal of Medical and Biological Research. Vol. 45. p. 875-890. 2012.

-Reidy, P. T.; Walker, D. K.; Dickinson, J. M.; Gundermann, D. M.; Drummond, M. J.; Timmerman, K. L.; Fry, C. S.; Borack, M. S.; Cope, M. B.; Mukherjea, R.; Jennings, K; Volpi, E.; Rasmussen, B. B. Protein Blend Ingestion Following Resistance Exercise Promotes Human Muscle Protein Synthesis. The Journal of Nutrition. Vol. 143. p. 410-416. 2013.

-Rose, A. J.; Alsted, T. J.; Jensen, T.E.; Kobbero, J.B.; Maarbjerg, S. J.; Jensen, J.; Richter, E. A. A. Ca(2+)-calmodulin-eEF2K-eEF2 signalling cascade, but not AMPK, contributes to the suppression of skeletal muscle protein synthesis during contractions. J Physiol. Vol. 587. p. 1547-1563. 2009.

-Slater, G; Phillips, S. M. Nutrition guidelines for strength sports: Sprinting, weightlifting, throwing events, and bodybuilding. Journal of Sports Sciences. Vol. 29. p. 67-77. 2011.

-Staples, A. W.; Burd, N. A.; West, D. W. D.; Currie, K. D.; Atherton, P. J.; Moore, D. R.; Rennie, M. J.; Macdonald, M. J.; Baker, S. K.; Phillips, S. M. Carbohydrate Does Not Augment Exercise-Induced Protein Accretion versus Protein Alone. Medicine & Science in Sports & Exercise. 2011.

-Stark, M.; Lukaszuk, J.; Prawitz, A.; Salacinski, A. Protein timing and its effects on muscular hypertrophy and strength in individuals engaged in weight-training. Journal of International Society Sports Nutrition. Vol. 9. Num. 1. 2012.

-Svanberg, E.; Jefferson, L. S.; Lundholm, K.; Kimball, S. R. Postprandial stimulation of muscle protein synthesis is independent of changes in insulin. American Journal of Physiology. Vol. 272. p. 841-847. 1997.

-Tang, J. E.; Phillips, S. M. Maximizing muscle protein anabolism: the role of protein quality. Current Opinion in Clinical Nutrition and Metabolic Care. Vol. 12. p. 66-71. 2009.

-Tipton, K. D. Efficacy and consequences of very-high-protein diets for athletes and exercisers. Proc Nutr Soc. Vol. 70. Num. 2. p. 205-214. 2011.

-Van Loon, L. J. C. Is There a Need for Protein Ingestion During Exercise? Sports Medicine. Vol. 44. p. 105-111. 2014.

-Walker, D. K.; Dickinson, J. M.; Timmerman, K. L.; Drummond, M. J.; Reidy, P.T.; Fry, C. S.; Gundermann, D. M.; Rasmussem, B. B. Exercise, Amino Acids and Aging in the control of human muscle protein synthesis. Medicine & Science & Sports Exercise. Vol. 43. Num. 12. p. 2249-2258. 2011.

-West, D. W. D.; Burd, N. A.; Coffey, V. G.; Baker, S. K.; Burke, L. M.; Hawley, J. A.; Moore, D. R.; Stellingwerff, T.; Phillips, S. M. Rapid aminoacidemia enhances myofibrillar protein synthesis and anabolic intramuscular signaling responses after resistance exercise. Am J Clin Nutr. Vol. 94. p. 795-803. 2011.

-Wilkinson, S. B.; Tarnopolsky, M. A.; Macdonald, M. J.; Macdonald, J. R.; Armstrong, D.; Phillips, S. M. Consumption of fluid skim milk promotes greater muscle protein accretion after resistance exercise than does consumption of an isonitrogenous and isoenergetic soy-protein beverage. American Journal of Clinical Nutrition. Vol. 85. p. 1031-1040. 2007.

Publicado
2016-03-04
Como Citar
Paes, S. T. (2016). Efeitos do consumo proteico sobre a hipertrofia ocasionada pelo treinamento resistido: uma visão atual. RBNE - Revista Brasileira De Nutrição Esportiva, 10(55), 11-23. Recuperado de https://www.rbne.com.br/index.php/rbne/article/view/595
Seção
Artigos Científicos - Original