Perfil da produção científica sobre suplementação de creatina na base de dados index Web of Science (1950-2024)
Resumo
Introdução: A suplementação de creatina é uma das substâncias ergogênicas mais estudadas com eficácia comprovada em exercícios intermitentes de alta intensidade e no treinamento de força. Objetivo: Conduzir uma análise bibliométrica para identificar os temas mais investigados, os artigos mais citados, os periódicos, países e pesquisadores com maior produção científica sobre suplementação de creatina, na base de indexação Web of Science. Materiais e Métodos: A palavra-chave "creatine supplementation" foi utilizada para buscar artigos publicados com esse tema no título, resumo e/ou palavras-chave. A coleta de dados foi realizada em 31 de dezembro de 2024. Resultados: A produção científica sobre suplementação de creatina teve um crescimento notável a partir do início da década de 1990, com um aumento exponencial no século XXI. A Universidade de São Paulo (USP), no Brasil (n = 178), lidera em número de publicações institucionais, enquanto os Estados Unidos (n = 1.364) é o país mais produtivo. A revista Nutrients (n = 226) é o periódico com maior número de artigos publicados, e Darren Candow (n = 70) destaca-se como o pesquisador mais prolífico. A área de Ciências do Esporte (n = 1.359) concentra o maior volume de investigações. Conclusão: A maior parte da produção científica sobre suplementação de creatina está voltada para a melhoria do desempenho esportivo. O tema desperta interesse global, com contribuições significativas de diferentes países e pesquisadores.
Referências
-Andres, S.; Ziegenhagen, R.; Trefflich, I.; Pevny, S.; Schultrich, K.; Braun, H.; Schänzer, W.; Hirsch-Ernst, K.I.; Schäfer, B.; Lampen, A. Creatine and creatine forms intended for sports nutrition. Molecular Nutrition and Food Research. Vol. 61. Num. 6. 2017. p. 1-18. https://doi.org/10.1002/mnfr.201600772
-Arazi, H.; Eghbali, E.; Suzuki, K. Creatine supplementation, physical exercise and oxidative stress markers: A review of the mechanisms and effectiveness. Nutrients. Vol. 13 Num. 3. 2021. p. 1-17. https://doi.org/10.3390/nu13030869
-Bangsbo, J.; Mohr, M.; Krustrup, P. Physical and metabolic demands of training and match-play in the elite football player. Journal of Sports Sciences. Vol. 24. Num. 7. 2006. p. 665-674. https://doi.org/10.1080/02640410500482529
-Bonilla, D.A.; Kreider, R.B.; Petro, J.L.; Romance, R.; García-Sillero, M.; Benítez-Porres, J.; Vargas-Molina, S. Creatine enhances the effects of cluster-set resistance training on lower-limb body composition and strength in resistance-trained men: A pilot study. Nutrients. Vol. 13. Num. 7. 2021. p. 1-18. https://doi.org/10.3390/nu13072303
-Bonilla, D.A.; Stout, J.R.; Candow, D.G.; Jiménez-García, J.D.; Gómez-Miranda, L.M.; Ortiz-Ortiz, M.; Forbes, S.C.; Ostojic, S.M.; Vargas-Molina, S.; Kreider, R.B. The power of creatine plus resistance training for healthy aging: enhancing physical vitality and cognitive function. Frontiers in Physiology. Num. 15. 2024. p. 1-9. https://doi.org/10. 3389/fphys.2024.1496544
-Butts, J.; Jacobs, B.; Silvis, M. Creatine use in sports. Sports Health. Num. 10. Vol. 1, 2018. p. 31-34. https://doi.org/10.1177/194173811 773 7248
-Campos, F.A.D.; Bertuzzi, R.; Dourado, A.C.; Santos, V.G.F.; Franchini, E. Energy demands in taekwondo athletes during combat simulation. European Journal of Applied Physiology. vol. 112. Num. 4. 2012. p. 1221-1228. https://doi.org/10.1007/s00421-011-2071-4
-Carney, D.N.; Gazdar, A.F.; Bepler, G.; Guccion, J.G.; Marangos, P.J.; Moody, T.W.; Zweig, M.H.; Minna, J.D. Establishment and identification of small cell lung cancer cell lines having classic and variant features. Cancer Research. Vol. 45. Num. 6. 1985. p. 2913-2923. https://doi.org/10.1016/s0169-5002(86)8 0023-x
-Coimbra, D.R.; Dominski, F.H.; Brandt, R.; Bevilacqua, G.G.; Andreato, L.V.; Andrade, A. Twenty years of scientific production in sport and exercise psychology journals: A Bibliometric Analysis in Web of Science. Revista de Psicologia Del Deporte. Vol. 31. Num. 1. 2022. p. 245-261.
-Contreras-Barraza, N.,;Madrid-Casaca, H.; Salazar-Sepúlveda, G.; Garcia-Gordillo, M.Á.; Adsuar, J.C.; Vega-Muñoz, A. Bibliometric analysis of studies on coffee/caffeine and sport. Nutrients. Vol. 13. Num. 9. 2021. p. 1-14. https://doi.org/10.3390/nu13093234
-Donthu, N.; Kumar, S.; Mukherjee, D.; Pandey, N.; Lim, W.M. How to conduct a bibliometric analysis: An overview and guidelines. Journal of Business Research. Vol. 133. Num. March. 2021. p. 285-296. https://doi.org/10.1016/ j.jbusres.2021.04.070
-Fernández-Landa, J.; Santibañez-Gutierrez, A.; Todorovic, N.; Stajer, V.; Ostojic, S.M. Effects of creatine monohydrate on endurance performance in a trained population: A systematic review and meta-analysis. Sports Medicine, Vol. 53. Num. 5. 2023. p. 1017-1027. https://doi.org/10.1007/s40279-023-01823-2
-Forbes, S.C.; Candow, D.G. Creatine and strength training in older adults: an update. Translational Exercise Biomedicine. Vol. 1. Num. 3. 2024. p. 212-222. https://doi.org/10. 1515/teb-2024-0019
-Forbes, S.C.; Candow, D.G.; Neto, J.H.F.; Kennedy, M.D.; Forbes, J.L.; Machado, M.; Bustillo, E.; Gomez-Lopez, J.; Zapata, A.; Antonio, J. Creatine supplementation and endurance performance: surges and sprints to win the race. Journal of the International Society of Sports Nutrition. Vol. 20. Num. 1. 2023. p. 209-228 https://doi.org/10.1080/15502783.20 23.2204071
-Franchini, E.; Gutierrez-Garcia, C.; Izquierdo, E. Olympic combat sports research output in the Web of Science: A sport sciences centered analysis Submission. Ido Movement for Culture. Journal of Martial Arts Anthropology. vol. 18. Num. 3. 2018. p. 21-27. https://doi.org/10. 14589/ido.18.3.
-Gontijo, L.P.; Machado Araújo, E.; Santos, P. A.; Pinheiro Barbosa, L.; Figueiredo, L.S.; Oliveira Castro, H.; Aguiar, S.S. Top 50 most-cited articles in caffeine and exercise: contributions for professionals and researchers. Revista Brasileira de Prescrição e Fisiologia do Exercício. São Paulo. Vol. 16. Num. 106. 2022. p. 663-676. http://www.rbpfex.com.br/index.php/rbpfex/article/view/2667
-Haff, G.G. Sport Science. Strength and Conditioning Journal. Vol. 32. Num. 2. 2010. p. 33-45.
-Hall, M.; Manetta, E.; Tupper, K. Creatine supplementation: An update. Current Sports Medicine Reports. Vol. 20. Num. 7. 2021. p. 338-344. https://doi.org/10.1249/JSR. 000000 0000000863
-Harris, R.C.; Soderlund, K.; Hultman, E. Elevation of creatine in resting and exercised muscle of normal subjects by creatine supplementation. Clinical Science. Vol. 83. Num. 3. 1992. p. 367-374. https://doi.org/10.1 042/cs0830367
-Hultman, E.; Söderlund, K.; Timmons, J.A.; Cederblad, G.; Greenhaff, P.L. Muscle creatine loading in men. Journal of Applied Physiology. Vol. 81. Num. 1. 1996. p. 232-237. https://doi.org/10.1152/jappl.1996.81.1.232
-Ibáñez, A.P.; Gil, J.M.; Chenoll, M.P. Bibliometric study of scientific production on handball. Movimento. Vol. 26. 2020. p. 1-20. https://doi.org/10.22456/1982-8918.101908
-Jagim, A.R.; Kerksick, C.M. Creatine supplementation in children and adolescents. Nutrients. Vol. 13. Num. 2. 2021. p. 1-17. https://doi.org/10.3390/nu13020664
-Khan, A.; Choudhury, N.; Uddin, S.; Hossain, L.; Baur, L.A. Longitudinal trends in global obesity research and collaboration: A review using bibliometric metadata. Obesity Reviews. Vol. 17. Num. 4. 2016. p. 377-385. https://doi.org/ 10.1111/obr.12372
-Kiss, A.; Temesi, Á.; Tompa, O.; Lakner, Z.; Soós, S. Structure and trends of international sport nutrition research between 2000 and 2018: bibliometric mapping of sport nutrition science. Journal of the International Society of Sports Nutrition. Vol. 18. Num. 1. 2021. p. 1-17. https://doi.org/10.1186/s12970-021-00409-5
-Kreider, R.B.; Kalman, D.S.; Antonio, J.; Ziegenfuss, T.N.; Wildman, R.; Collins, R.; Candow, D.G.; Kleiner, S.M.; Almada, A.L.; Lopez, H.L. International society of sports nutrition position stand: Safety and efficacy of creatine supplementation in exercise, sport and medicine. Journal of the International Society of Sports Nutrition. Vol. 14. Num. 1. 2017. p. 1-18. https://doi.org/10.1186/s12970-017-0173-z
-Kreider, R.B.; Stout, J.R. Creatine in health and disease. Nutrients. Vol. 13. Num. 2. 2021. p. 1-28. https://doi.org/10.3390/nu13020447
-Li, X.-L.; Gao, R.-X.; Zhang, Q.; Li, A.; Cai, L.-N.; Zhao, W.-W.; Gao, S.-L.; Wang, Y.; Yue, J. A bibliometric analysis of neuroimaging biomarkers in Parkinson disease based on Web of Science. Journal of Engineering Research. Vol. 11. Num. 2. 2023. p. 226-235. https://doi.org/10.36909/jer.12239
-Lou, Y.; Sun, N.; Zhang, M.; Qiu, Y.; Wang, J.; & Chen, J. Trends in exercise for hypertension: a bibliometric analysis. Frontiers in Cardiovascular Medicine, Vol. 10. 2023. p. 1-15. https://doi.org/10.3389/fcvm.2023.1260569
-Lui, J.C.L.; Lam, W.Y.H.; Chu, C.H.; Yu, O.Y. Global research trends in the detection and diagnosis of dental caries: A bibliometric analysis. International Dental Journal, Vol. 00. Num. 00, 2024. p. 1-10. https://doi.org/10.1016/j.identj.2024.08.010
-Martín-Martín, A.; Orduna-Malea, E.; Delgado López-Cózar, E. Coverage of highly-cited documents in Google Scholar, Web of Science, and Scopus: a multidisciplinary comparison. Scientometrics, Vol. 116. Num. 3. 2018. p. 2175-2188. https://doi.org/10.1007/s11192-018-2820-9
-Maughan, R.J.; Burke, L.M.; Phillips, S.M.; Rawson, E.S.; Walsh, N.P.; Garthe, I.; Geyer, H.; Meeusen, R.; Shirreffs, S.M.; Spriet, L.L.; Stuart, M.; Vernec, A.; Currell, K.; Budgett, R. G.M.; Ljungqvist, A.; Mountjoy, M. IOC Consensus Statement: Dietary Supplements and the High-Performance Athlete. International Journal of Sport Nutrition and Exercise Metabolism, Vol. 28. 2018. p. 104-125. https://doi.org/10.1136/bjsports-2018-099027
-Plakias, S.; Tsatalas, T.; Mina, M.A.; Kokkotis, C.; Kellis, E.; Giakas, G. A bibliometric analysis of soccer biomechanics. Applied Sciences (Switzerland), Vol. 14. Num. 15. 2024. p. 1-15. https://doi.org/10.3390/app14156430
-Prieto, J.; Gómez, M.-Á.; Sampaio, J. A bibliometric review of the scientific production in handball. Cuadernos de Psicología Del Deporte, Vol. 15. 2015. p. 145-154. http://revistas.um.es/cpd
-Reis, F.D.G.; Franchini, E.; Capraro, A.M. Profile of scientific productions on judo : an analysis of the Web of Science database (1956 - 2019). Ido Movement for Culture. . Journal of Martial Arts Anthropology. Vol. 22. Num. 3. 2022. p. 51-59. https://doi.org/10.14589 /ido.22.3.8
-Rodriguez, N.R.; DiMarco, N.M.; Langley, S. Nutrition and Athletic Performance. Medicine and Science in Sports and Exercise. Vol. 41Num. 3. 2016. p. 709-731. https://doi.org/ 10.1249/MSS.0000000000000852
-Sandkühler, J.F.; Kersting, X.; Faust, A.; Königs, E.K.; Altman, G.; Ettinger, U.; Lux, S.; Philipsen, A.; Müller, H.; Brauner, J. The effects of creatine supplementation on cognitive performance-a randomised controlled study. BMC Medicine. Vol. 21. Num. 1. 2023. p. 1-16. https://doi.org/10.1186/s12916-023-03146-5
-Santacruz, L.; Arciniegas, A.J.L.; Darrabie, M.; Mantilla, J.G.; Baron, R.M.; Bowles, D.E.; Mishra, R.; Jacobs, D.O. Hypoxia decreases creatine uptake in cardiomyocytes, while creatine supplementation enhances HIF activation. Physiological Reports, Vol. 5. Num. 16. 2017. p. 1-10. https://doi.org/10. 14814/phy2.13382
-Silva Duarte, J.D.R.; Salinas, J.A.R.; Souza, R.F. Kickboxing scientific production indexed on PubMed: productivity, topics and citations. Ido Movement for Culture Journal of Martial Arts Anthropology. Vol. 24. Num. 3. 2024. p. 23-31. https://doi.org/10.14589/ido.24.3.3
-Salles Painelli, V.; Alves, V.T.; Ugrinowitsch, C.; Benatti, F.B.; Artioli, G.G.; Lancha, A.H.; Gualano, B.; Roschel, H. Creatine supplementation prevents acute strength loss induced by concurrent exercise. European Journal of Applied Physiology. Vol. 114. Num. 8. 2014. p. 1749-1755. https://doi.org/10.1007/ s00421-014-2903-0
-Scott, M.L. Studies on the enlarged hock disorder (Perosis) in turkeys: three figures. The Journal of Nutrition. Vol. 30. Num. 6. 1950. p. 846-855. https://doi.org/10.3382/ps.0300846
-Sofyan, D.; Abdullah, K.H.; Gazali, N. A bibliometric review of basketball game: publication trends over the past five decades. ASM Science Journal. Vol. 17. 2022. p. 1-12. https://doi.org/10.32802/ASMSCJ.2022.1277
-Sousa, J.L.; Hernández-Beltrán, V.; Louro, H.; Gamonales, J.M. Evolution of the documents related to the study of taekwondo sports performance: a bibliometric review. Retos. Vol. 60. 2024. p. 539-551.
-Spencer, M.; Bishop, D.; Dawson, B.; Goodman, C. Physiological and metabolic responses of repeated-sprint activities specific to field-based team sports. Sports Medicine, Vo. 35. Num. 12. 2005. p. 1025-1044.
-Sun, J.; Guo, F.; Ran, J.; Wu, H.; Li, Y.; Wang, M.; Wang, X. Bibliometric and visual analysis of global research on taurine, creatine, carnosine, and anserine with metabolic syndrome: From 1992 to 2022. Nutrients. Vol. 15. Num. 15. 2023. p. 1-15. https://doi.org/10.3390/ nu15 153374
-Sweileh, W.M.; Al-Jabi, S.W.; Sawalha, A.F.; Zyoud, S.H. Bibliometric analysis of nutrition and dietetics research activity in Arab countries using ISI Web of Science database. SpringerPlus. Vol. 3. Num. 1. 2014. p. 1-7. https://doi.org/10.1186/2193-1801-3-718
-Varillas-Delgado, D. Association of genetic profile with muscle mass gain and muscle injury prevention in professional football players after creatine Supplementation. Nutrients. Vol. 16. Num. 15. 2024. p. 1-20. https://doi.org/10.3390 /nu16152511
-Wallimann, T.; Uwe, M.T. The creatine kinase system and pleiotropic effects of creatine. Amino Acids, Vol. 40. 2011. p. 1271-1296. https://doi.org/10.1007/s00726-011-0877-3
-Wang, W.; Wu, Z.; Dai, Z.; Yang, Y.; Wang, J.; Wu, G. Glycine metabolism in animals and humans: implications for nutrition and health. Amino Acids. Vol. 45. 2013. p. 463-477. https://doi.org/10.1007/s00726-013-1493-1
-Wax, B.; Kerksick, C.M.; Jagim, A.R.; Mayo, J.J.; Lyons, B.C.; Kreider, R.B. Creatine for exercise and sports performance, with recovery considerations for healthy populations. Nutrients. Vol. 13. Num. 6. 2021. p. 1-42.
-Wu, G.; Bazer, F.W.; Davis, T.A.; Kim, S.W.; Li, P.; Marc Rhoads, J.; Carey Satterfield, M.; Smith, S.B.; Spencer, T.E.; Yin, Y. Arginine metabolism and nutrition in growth, health and disease. Amino Acids. Vol. 37. Num. 1. 2009. p. 153-168. https://doi.org/10.1007/s00726-008-0210-y
-Wu, H.; Sun, Z.; Tong, L.; Wang, Y.; Yan, H.; Sun, Z. Bibliometric analysis of global research trends on male osteoporosis: a neglected field deserves more attention. Archives of Osteoporosis. Vol. 16. Num. 1. 2021. p. 1-14. https://doi.org/10.1007/s11657-021-01016-2
-Wu, S.; Chen, K.; Hsu, C.; Chen, H.; Chen, J.; Yu, S.; Shiu, Y. Creatine supplementation for muscle growth: a scoping review of randomized clinical trials from 2012 to 2021. Nutrients. Vol. 14. Num. 1255. 2022. p. 1-17.
-Wuertz, S.; Reiser, S. Creatine: A valuable supplement in aquafeeds? Reviews in Aquaculture, Vol. 15. Num. 1. 2023. p. 292-304. https://doi.org/10.1111/raq.12717
-Xu, F.; Zeng, J.; Liu, X.; Lai, J.; Xu, J. Exercise-induced muscle damage and protein intake: A bibliometric and visual analysis. Nutrients. Vol. 14. Num. 20. 2022a. p. 1-20. https://doi.org/10. 3390/nu14204288
-Xu, H.; Cheng, X.; Wang, T.; Wu, S.; Xiong, Y. Mapping neuroscience in the field of education through a bibliometric analysis. Brain Sciences. Vol. 12. Num. 11. 2022. p. 1-23. https://doi.org/ 10.3390/brainsci12111454
-Zupic, I.; Čater, T. Bibliometric methods in management and organization. Organizational Research Methods. Vol. 18. Num. 3. 2015. p. 429-472. https://doi.org/10.1177/109442 8114 562629
Copyright (c) 2025 Marcelo Augusto Alves de Oliveira, Jonatas Deivyson Reis da Silva Duarte, Michelle Jalousie Kommers, Carlos Alexandre Fett, Waléria Christiane Rezende Fett

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Autores que publicam neste periódico concordam com os seguintes termos:
- Autores mantém os direitos autorais e concedem ao periódico o direito de primeira publicação, com o trabalho simultaneamente licenciado sob a Creative Commons Attribution License BY-NC que permitindo o compartilhamento do trabalho com reconhecimento da autoria do trabalho e publicação inicial neste periódico.
- Autores têm autorização para assumir contratos adicionais separadamente, para distribuição não-exclusiva da versão do trabalho publicada neste periódico (ex.: publicar em repositório institucional ou como capítulo de livro), com reconhecimento de autoria e publicação inicial neste periódico.
- Autores têm permissão e são estimulados a publicar e distribuir seu trabalho online (ex.: em repositórios institucionais ou na sua página pessoal) a qualquer ponto antes ou durante o processo editorial, já que isso pode gerar alterações produtivas, bem como aumentar o impacto e a citação do trabalho publicado (Veja O Efeito do Acesso Livre).
