Effects of gamma aminobutyric acid supplementation associated with physical exercise on cardiovascular responses and subjective perception of effort in obese women
Abstract
Gamma-aminobutyric acid (GABA) is an inhibitory amino acid in the central nervous system, with the premise of being a supplement to enhance physical recovery. Among the investigated actions is it possible to cite: reductions in blood pressure, improved sleep quality, and reduced anxiety levels. Objective: To investigate the effects and benefits of oral GABA supplementation combined with physical exercise on responses to physical effort during 12 weeks of combined training (aerobic and strength) in women with obesity. The study included 26 female volunteers aged 18 to 59 years with a BMI ≥ 30 kg/m2, which were randomized into two groups: GABA and placebo. The combine physical training was carried out for 12 weeks, on three alternating days for 50 minutes. Heart rate (HR) during the exercise session was measured using a heart rate monitor, and subjective perceived exertion (RPE) was assessed on a scale of 0 to 10. Results and Discussion: GABA supplementation did not result in significant differences in RPE between the placebo group (RPE=6) and the GABA group (RPE=7). There were also no significant differences in HR between the groups (placebo: 146 bpm, and GABA: 148 bpm). The participation rate was 88.9% for the GABA group and 84.3% for the placebo group. The 12 weeks of combined training associated with GABA supplementation did not affect the RPE and HR of women with obesity.
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